Efficacy of 3 Monthly versus Monthly Zoledronic Acid on Bone Metastasis
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چکیده
منابع مشابه
Six monthly intravenous zoledronic acid in childhood osteoporosis
Childhood osteoporosis can be treated with intravenous bisphosphonates in order to improve bone mass and density. The aims of this study were to evaluatethe safety and efficacy of six-monthly zoledronic acid (ZA) in children with osteoporosis. A retrospective cohort study of 27 patients (16 males and 11 females) weretreated with six-monthly ZA (0.05mg/kg/dose) for a minimum of one year.17 patie...
متن کاملA phase I dose-ranging trial of monthly infusions of zoledronic acid for the treatment of osteolytic bone metastases.
Bisphosphonates are potent inhibitors of bone resorption and provide a therapeutic benefit for patients with bone metastases. Zoledronic acid is a highly potent, nitrogen-containing bisphosphonate. In the present trial, we assessed the safety and tolerability of increasing doses of zoledronic acid and its effects on urinary markers of bone resorption in cancer patients with bone metastases. Fif...
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Objective: This post hoc analysis evaluated the efficacy of lurasidone in patients with acute schizophrenia with prominent positive symptoms. Methods: Patient-level data were pooled from 5 similarly designed, multiregional, randomized, double-blind, placebocontrolled, 6-week studies of fixed-dose lurasidone (40, 80, 120, or 160 mg/d) in adult patients with acute schizophrenia. Patients with pro...
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AIM Zoledronic acid (ZA) reduces the risk of skeletal-related events (SREs) in castration-resistant prostate cancer (CRPC) with bone metastasis and improves quality of life. It remains unclear when clinicians should initiate ZA treatment. PATIENTS AND METHODS Hormone-naïve patients were randomized to a combined androgen blockade (CAB) group or CAB with ZA group (CAB-ZA) based on Gleason score...
متن کاملTwelve-monthly versus six-monthly radiological screening for active case-finding of tuberculosis: a randomised controlled trial.
BACKGROUND The incidence of tuberculosis has increased among South African gold miners despite comprehensive control programmes, including a radiological screening programme. No data are available as to the optimal frequency of screening. The aim of this study was to compare 6-monthly and 12-monthly radiological screening for active tuberculosis case-finding. METHODS Employees of a gold minin...
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ژورنال
عنوان ژورنال: Tumori Journal
سال: 2021
ISSN: 0300-8916,2038-2529
DOI: 10.1177/03008916211012338